timsOmni™

proteoElute™

Optimized nanoflow workflows for high throughput and ultra sensitive multiomics experiments

The proteoElute™ nano‑UHPLC system from Bruker is designed for ultra‑sensitive, high‑throughput multi‑omics workflows—perfectly optimized for TIMS‑enabled mass spectrometers via Compass® HyStar integration. It features rugged ceramic valves, proprietary proteoTrap™ columns, and innovative injector‑needle wash, reducing carry‑over by up to 3×. TwinScape™ technology delivers real‑time monitoring and predictive maintenance, minimizing downtime and ensuring data integrity. Its eco‑friendly design cuts solvent use by up to 80% per wash and ships in 100% recycled packaging. Built for trace samples like single‑cell proteomics, immunopeptidomics, and metaproteomics, proteoElute™ delivers robustness, efficiency, and sustainability in one powerful LC solution

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timsOmni™

Key Features

  • Robust Operation
    Ceramic valves, High- and Low-Pressure filters
  • Self-check Features
    Fully automated system check during idle time and sample table
  • Reduced Overhead Time
    New elution modes
  • Environmentally Protected Fluidic Path
    Reproducible ultra-high precision gradient
  • Advanced TwinScape Integration
    System monitoring and proactive maintenance
  • Reduced Carryover
    3x less with the new Bruker injection port
  • Reduced Solvent Consumption
    Up to 5x less with the new wash procedures
  • New proteoTrap Column
    Minimize sample loss during trapping/elution
  • ACT 2.0 Label
    Removal of most fluorinated plastic, reduced
    system weight

TIMS-MS

Elevate MS and MSn Sensitivity to New Heights

Ceramic Valves

Experience unparalleled full scan MS and MSn sensitivity by leveraging the omnidirectional, multistage MSn eXd workflow for enrichment and signal amplification, thanks to the unique Omnitrap® platform design.

TwinScape™

New, durable ceramic valves developed by IDEX for longevity and maximum robustness.

Accuracy

TwinScape™ allows for continuous monitoring of your LC-MS system, ensuring peak efficiency and proactive maintenance.

Reduced Carryover

Innovative injector port and injection needle wash for 3x less sample-to-sample carryover.

Environmentally Friendly

Up to 80% reduced solvent consumption per injection path wash cycle and ships in 100% recycled packaging.

Environmentally Friendly

The proteoElute™ simplifies your workflow by ensuring data integrity, limiting your environmental footprint, and seamlessly integrating with your TIMS-enabled mass spectrometers via HyStar. The proven HyStar engine is further optimized to reduce loading and equilibration time, leading to faster injection-to-injection performance.

Environmentally Friendly

TwinScape Technology: Continuous monitoring of key instrument parameters in real-time, monitoring performance and enabling proactive maintenance.
Ceramic Valves: Developed by IDEX for longevity and maximum robustness
Reduced Carryover: Innovative injector port and injection needle wash for 3x less sample-to-sample carryover.
Limit your environmental footprint. Environmentally Friendly Design: Up to 80% reduced solvent consumption per injection path wash cycle and ships in 100% recycled packaging.

Unmatched Robustness and Efficiency

The proteoElute™ optimizes nanoflow workflows for high throughput and ultra-sensitive multiomics experiments. It offers enhanced injection precision through a newly designed wash port and optimized washing routine, minimizing sample-to-sample carryover.

The system ensures reliable results for low input applications such as single-cell proteomics and immunopeptidomics. The innovative piston wash pump and new injection port design significantly reduce hazardous organic waste, achieving up to 80% reduction in solvent consumption.

A trap column not only protects the analytical column and extends its lifetime but also enables on-column enrichment for improved analyte detection. For the proteoElute, Bruker has developed the proteoTrap™, a new trap column in collaboration with GL Sciences.

The carefully selected stationary phase effectively traps hydrophilic and hydrophobic analytes leading to increased sequence coverage and identification rates, even at ultra-low concentrations. Bruker’s new proteoTrap™ column delivers intelligent protection and optimized performance for your low-input proteomics needs.

The proteoElute™: Democratizing Proteomics

The proteoElute™ is designed to deliver peace of mind when analyzing precious samples. It integrates seamlessly with your TIMS-enabled mass spectrometers, optimizing nanoflow workflows for high throughput and ultra-sensitive multiomics experiments.

The system’s robustness is achieved through biocompatible ceramic valve technology and strategically integrated porous metal filters across the pressurized solvent lines. The environmentally friendly design helps minimize hazardous waste, making it ideal for sustainable research practices.

For LC systems, Bruker’s TwinScape software tracks key performance indicators such as pressure stability, flow consistency, gradient integrity, and autosampler behavior. As part of routine QC runs, it also displays LC pump pressure readings, helping to identify early signs of blockages, leaks, or flow deviations.

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